NMR determination of oligonucleotide structure

Curr Protoc Nucleic Acid Chem. 2001 May:Chapter 7:Unit 7.2. doi: 10.1002/0471142700.nc0702s00.

Abstract

This unit provides an overview of the use of NMR to determine oligonucleotide structure. It covers basic NMR spectral properties, acquisition of interproton distance restraints and torsion angle restraints, structure refinement, assessment of the quality of the structure obtained. Software programs used in the process are also described.

Publication types

  • Research Support, N.I.H., Extramural
  • Review

MeSH terms

  • Computer Simulation
  • Magnetic Resonance Spectroscopy / methods*
  • Models, Molecular
  • Nucleic Acids / chemistry
  • Oligonucleotides / chemistry*
  • Protons

Substances

  • Nucleic Acids
  • Oligonucleotides
  • Protons