Objective: To review the latest development of amniotic fluid-derived stem cell(AFS) and to predict its future application.
Methods: The recent articles about AFS were extensively reviewed. The origin,culture,identification,and directional differentiation as well as future application of AFS were summarized and discussed.
Results: In 1993, AFS were thought to be exist possibly, and it was confirmed in recent years. AFS have some surface markers like other stem cells, and has multi-differentiated potential and extensive future application in cell therapy and tissue engineering approaches.
Conclusion: As a new stem cell, AFS remains to be further researched.