Clinical decision support (CDS) rules monitoring adherence to guidelines for secondary prevention of acute myocardial infarction (AMI) have been in use at BJC HealthCare's academic facility for five years. The alert web response form for these rules was enhanced to facilitate documentation of contraindications for ACE/ARB, beta blocker, aspirin, and lipid-lowering medications. An analysis of the impact of these enhancements and the changes to pharmacy workflow are presented here.