Abstract
Causes of primary ovarian failure are reviewed, focusing specifically on cancer treatment-related modalities. Strategies and future directions for protection of the ovaries during cancer therapy, including ovarian transposition, and conformal radiation techniques are presented.
MeSH terms
-
Antineoplastic Agents / adverse effects*
-
Antineoplastic Agents / therapeutic use
-
Dose-Response Relationship, Drug
-
Dose-Response Relationship, Radiation
-
Female
-
Humans
-
Infertility, Female / etiology*
-
Infertility, Female / prevention & control
-
Male
-
Neoplasms / complications
-
Neoplasms / drug therapy*
-
Neoplasms / radiotherapy*
-
Primary Ovarian Insufficiency / etiology*
-
Primary Ovarian Insufficiency / prevention & control
-
Radiation Injuries / etiology*
-
Radiation Injuries / prevention & control
-
Radiotherapy, Conformal / adverse effects*