Peritonitis due to Mycobacterium avium complex in patients with AIDS: report of five cases and review of the literature

Int J Infect Dis. 2009 Mar;13(2):285-90. doi: 10.1016/j.ijid.2008.07.016. Epub 2008 Oct 26.

Abstract

Background: Mycobacterium avium complex (MAC) often causes disseminated infection in patients at an advanced stage of HIV infection; however, peritonitis associated with disseminated MAC infection is rare.

Methods: In this report, we describe five cases of MAC peritonitis in AIDS patients at our hospital, and analyze these cases alongside 11 previously published cases found in the literature.

Results: Most of the AIDS patients with MAC peritonitis had CD4 counts of <50 cells/microl and elevated alkaline phosphatase levels. Other than ascites, MAC was also isolated from other sterile and non-sterile sites. Of note, six patients (37.5%) presented with chylous ascites.

Conclusions: Despite therapy, MAC peritonitis is associated with a grave outcome.

Publication types

  • Case Reports
  • Review

MeSH terms

  • AIDS-Related Opportunistic Infections / microbiology*
  • Adult
  • Female
  • HIV Infections / complications*
  • HIV Infections / virology
  • HIV-1
  • Humans
  • Male
  • Middle Aged
  • Mycobacterium avium Complex / isolation & purification*
  • Mycobacterium avium-intracellulare Infection / complications*
  • Mycobacterium avium-intracellulare Infection / microbiology
  • Peritonitis / complications*
  • Peritonitis / microbiology*
  • Young Adult