Drug-induced movement disorders in children

Ann N Y Acad Sci. 2008 Oct:1142:72-84. doi: 10.1196/annals.1444.005.

Abstract

This article reviews the current state of knowledge of drug-induced movement disorders (DIMDs) in children. The objective is to aid clinicians who treat children with medications that may induce DIMDs, as well as specialists consulted on DIMDs. As with adults, the most common agents are dopaminergic and dopamine-blocking medications, and prescriptions for these agents have increased markedly in children. Unfortunately, most evidence-based reviews, including those from the Cochrane Collaboration cited here, have few systematic data to analyze. Many publications are small case series. This report attempts to provide useful information, with appropriate caution and discussion of the limitations of what we know.

Publication types

  • Review

MeSH terms

  • Akathisia, Drug-Induced / etiology
  • Akathisia, Drug-Induced / pathology
  • Akathisia, Drug-Induced / therapy
  • Antipsychotic Agents / adverse effects
  • Child
  • Dopamine Antagonists / adverse effects
  • Dyskinesia, Drug-Induced / etiology
  • Dyskinesia, Drug-Induced / pathology
  • Dyskinesia, Drug-Induced / therapy
  • Humans
  • Movement Disorders / etiology
  • Movement Disorders / pathology*
  • Movement Disorders / therapy*
  • Psychotropic Drugs / adverse effects

Substances

  • Antipsychotic Agents
  • Dopamine Antagonists
  • Psychotropic Drugs