Alterations in the intestinal microbiota and functional bowel symptoms

Yehuda Ringel; Ian M Carroll

doi:10.1016/j.giec.2008.12.004

Alterations in the intestinal microbiota and functional bowel symptoms

Gastrointest Endosc Clin N Am. 2009 Jan;19(1):141-50, vii. doi: 10.1016/j.giec.2008.12.004.

Authors

Yehuda Ringel¹, Ian M Carroll

Affiliation

¹ Division of Gastroenterology and Hepatology, University of North Carolina at Chapel Hill School of Medicine, 4107 BioInformatics Building, CB# 7080, 130 Mason Farm Road, Chapel Hill, NC 27599-7080, USA. ringel@med.unc.edu

PMID: 19232285
DOI: 10.1016/j.giec.2008.12.004

Abstract

Functional gastrointestinal disorders (FGIDs) are highly prevalent in Western countries yet no single mechanism or etiological agent that initiates IBS has been identified. Current research has implicated the intestinal microbiota with FGIDs. This article reviews the available literature/data regarding the intestinal microbiota and FGIDS. The possible relationships between the intestinal microbiota and the intestinal function and functional bowel symptoms are discussed.

Publication types

Review

MeSH terms

Animals
Anti-Bacterial Agents / therapeutic use
Colonic Diseases, Functional / drug therapy
Colonic Diseases, Functional / epidemiology
Colonic Diseases, Functional / microbiology*
Gastrointestinal Tract / drug effects
Gastrointestinal Tract / microbiology*
Gastrointestinal Tract / pathology
Humans
Irritable Bowel Syndrome / drug therapy
Irritable Bowel Syndrome / epidemiology
Irritable Bowel Syndrome / microbiology
Prevalence
Probiotics / therapeutic use
United States / epidemiology

Substances

Anti-Bacterial Agents