Know your APC

Blood. 2009 Jun 4;113(23):5699-700. doi: 10.1182/blood-2009-03-211292.

Abstract

The mechanism underscoring efficacy of APC in the treatment of sepsis is still unresolved. The dual nature of APC as a potent antithrombotic and cytoprotective agent complicates the task, but in this issue of Blood, Mosnier and colleagues offer a compelling solution and challenge the molecular underpinnings of APC function.

Publication types

  • Comment
  • Research Support, N.I.H., Extramural