Spontaneous control of viral replication during primary HIV infection: when is "HIV controller" status established?

Clin Infect Dis. 2009 Sep 15;49(6):982-6. doi: 10.1086/605504.

Abstract

Eight patients in the ANRS PRIMO cohort experienced early spontaneous viral control. Viral control was established a median of 6.2 months after primary human immunodeficiency virus type 1 infection and lasted a median of 4.1 years. Seven of the patients initially had detectable viral replication. For 4 patients, viral control was lost during follow-up.

Publication types

  • Multicenter Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • CD4-CD8 Ratio
  • Cohort Studies
  • Disease Progression
  • Female
  • HIV Infections / immunology*
  • HIV Infections / virology*
  • HIV-1 / physiology*
  • Humans
  • Male
  • Middle Aged
  • RNA, Viral / blood*
  • Remission, Spontaneous
  • Viral Load
  • Virus Replication*
  • Young Adult

Substances

  • RNA, Viral