Hypomelanosis of Ito with hemimegalencephaly

Dermatol Online J. 2009 Nov 15;15(11):12.

Abstract

Hypomelanosis of Ito is a neurocutaneous syndrome characterized by hypopigmented lesions occurring in streaks and whorls located on the trunk, head or extremities. The associated neurological manifestations include mental retardation, seizures, language disabilities and motor system dysfunction. Hemihypertrophy has also been described in this syndrome. We present a 3-month-old male infant with Hypomelanosis of Ito, hemi-hypertrophy and hemi-megalencephaly.

Publication types

  • Case Reports

MeSH terms

  • Developmental Disabilities / complications
  • Developmental Disabilities / diagnosis*
  • Follow-Up Studies
  • Humans
  • Hypopigmentation / complications
  • Hypopigmentation / genetics*
  • Hypopigmentation / physiopathology
  • Infant
  • Intellectual Disability / complications
  • Intellectual Disability / diagnosis
  • Magnetic Resonance Imaging
  • Male
  • Malformations of Cortical Development / complications
  • Malformations of Cortical Development / diagnosis
  • Malformations of Cortical Development / pathology*
  • Monitoring, Physiologic / methods
  • Risk Assessment
  • Seizures / complications
  • Seizures / diagnosis
  • Severity of Illness Index