Amorphous silicon-carbon alloys for efficient localized surface plasmon resonance sensing

Biosens Bioelectron. 2010 Jan 15;25(5):1199-203. doi: 10.1016/j.bios.2009.10.012. Epub 2009 Oct 29.

Abstract

This paper describes a novel platform for preparing localized surface plasmon resonance (LSPR) sensing surfaces. It is based on the coating of gold nanostructures deposited on glass with an amorphous silicon-carbon alloy overcoating. The interest in coating the Au NSs with an amorphous silicon-carbon alloy resides in the possibility of incorporating carboxyl functions directly onto the surface via Si-C covalent bonds. This permits the use of hyrdosilylation reactions to modify the sensor surface. The use of this multilayer structure for the detection of hybridization events is discussed.

Publication types

  • Evaluation Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alloys
  • Biosensing Techniques / instrumentation*
  • Carbon / chemistry*
  • DNA / chemistry*
  • DNA / genetics*
  • Equipment Design
  • Equipment Failure Analysis
  • In Situ Hybridization / instrumentation*
  • Reproducibility of Results
  • Sensitivity and Specificity
  • Silicon / chemistry*
  • Surface Plasmon Resonance / instrumentation*

Substances

  • Alloys
  • Carbon
  • DNA
  • Silicon