First autochthonous case of Rhinocladiella mackenziei cerebral abscess outside the Middle East

J Clin Microbiol. 2010 Feb;48(2):646-9. doi: 10.1128/JCM.01855-09. Epub 2009 Dec 9.

Abstract

Cerebral phaeohyphomycosis due to Rhinocladiella mackenziei is a severe infection in the middle east, resulting in nearly 100% mortality despite the application of combined surgical and antifungal therapy and occurring occasionally in otherwise healthy patients. We report the first case of brain infection in a middle-aged male in India, where R. mackenziei is not endemic.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antifungal Agents / pharmacology
  • Antifungal Agents / therapeutic use
  • Ascomycota / classification
  • Ascomycota / genetics
  • Ascomycota / isolation & purification*
  • Brain / diagnostic imaging
  • Brain / pathology
  • Brain Abscess / microbiology*
  • DNA, Fungal / chemistry
  • DNA, Fungal / genetics
  • DNA, Ribosomal Spacer / chemistry
  • DNA, Ribosomal Spacer / genetics
  • Fatal Outcome
  • Histocytochemistry
  • Humans
  • India
  • Male
  • Microbial Sensitivity Tests
  • Microscopy
  • Middle Aged
  • Molecular Sequence Data
  • Mycoses / diagnosis*
  • Mycoses / microbiology
  • Radiography
  • Sequence Analysis, DNA

Substances

  • Antifungal Agents
  • DNA, Fungal
  • DNA, Ribosomal Spacer

Associated data

  • GENBANK/GQ863214