Paradoxical tuberculosis associated immune reconstitution inflammatory syndrome presenting with chylous ascites and chylothorax in a HIV-1 infected child

Helena Rabie; Andrea Lomp; Pierre Goussard; Ettienne Nel; Mark Cotton

doi:10.1093/tropej/fmp141

Paradoxical tuberculosis associated immune reconstitution inflammatory syndrome presenting with chylous ascites and chylothorax in a HIV-1 infected child

J Trop Pediatr. 2010 Oct;56(5):355-8. doi: 10.1093/tropej/fmp141. Epub 2010 Jan 25.

Authors

Helena Rabie¹, Andrea Lomp, Pierre Goussard, Ettienne Nel, Mark Cotton

Affiliation

¹ Tygerberg Children's Hospital and University of Stellenbosch, Pediatrics and Child Health, South Africa. hrabie@sun.ac.za

PMID: 20100782
DOI: 10.1093/tropej/fmp141

Abstract

We present a case of tuberculosis (TB) paradoxical immune reconstitution inflammatory syndrome (IRIS) complicated by chylous ascites and chylothorax in a HIV-infected child. There are few descriptions of TB IRIS in children. This case extends the clinical spectrum of TB IRIS.

Publication types

Case Reports

MeSH terms

AIDS-Related Opportunistic Infections / complications
AIDS-Related Opportunistic Infections / drug therapy
AIDS-Related Opportunistic Infections / immunology
Antiretroviral Therapy, Highly Active
Child, Preschool
Chylothorax / complications*
Chylous Ascites / complications*
HIV Infections / complications*
HIV Infections / drug therapy
HIV Infections / immunology
HIV-1*
Humans
Immune Reconstitution Inflammatory Syndrome / etiology*
Male
Treatment Outcome
Tuberculosis / complications*
Tuberculosis / drug therapy
Tuberculosis / immunology