Abstract
Generation of free radicals in children after liver transplantation is multifactorial from ischemia-reperfusion injury, immunosuppression and post-transplant complications. Thus, this group is at higher risk of oxidative imbalance with molecular and clinical consequences. We discuss pathogenesis and ways of action against oxidative stress in liver transplant recipients.
Publication types
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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Antioxidants / therapeutic use
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Child
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Genetic Therapy
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Humans
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Immunosuppressive Agents / adverse effects
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Ischemic Preconditioning
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Liver Transplantation / adverse effects*
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Liver Transplantation / physiology
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Oxidative Stress*
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Reactive Oxygen Species
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Reperfusion Injury / etiology
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Reperfusion Injury / metabolism
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Reperfusion Injury / physiopathology*
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Reperfusion Injury / therapy
Substances
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Antioxidants
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Immunosuppressive Agents
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Reactive Oxygen Species