Haploinsufficiency of the IKZF1 (IKAROS) tumor suppressor gene cooperates with BCR-ABL in a transgenic model of acute lymphoblastic leukemia

Leukemia. 2010 Jun;24(6):1200-4. doi: 10.1038/leu.2010.63. Epub 2010 Apr 15.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Female
  • Flow Cytometry
  • Fusion Proteins, bcr-abl / physiology*
  • Genes, Tumor Suppressor / physiology*
  • Humans
  • Ikaros Transcription Factor / physiology*
  • Male
  • Mice
  • Mice, Inbred C57BL
  • Mice, Transgenic
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma / etiology*
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma / pathology*
  • Survival Rate

Substances

  • Ikaros Transcription Factor
  • Fusion Proteins, bcr-abl