Primary treatment of incomplete Kawasaki disease with infliximab and methylprednisolone in a patient with a contraindication to intravenous immune globulin

Pediatr Infect Dis J. 2010 Oct;29(10):978-9. doi: 10.1097/INF.0b013e3181e05564.

Abstract

Incomplete Kawasaki disease was diagnosed in a 3-year-old boy. Because intravenous immune globulin infusion was not tolerated, he was treated with infliximab and methylprednisolone. Coronary aneurysms were not visualized on initial or follow-up echocardiograms. To our knowledge, this is the first report to document the use of infliximab and methylprednisolone as first line therapy for Kawasaki disease.

Publication types

  • Case Reports

MeSH terms

  • Antibodies, Monoclonal / administration & dosage*
  • Child, Preschool
  • Coronary Aneurysm / diagnosis
  • Humans
  • Immunologic Factors / administration & dosage*
  • Infliximab
  • Male
  • Methylprednisolone / administration & dosage*
  • Mucocutaneous Lymph Node Syndrome / diagnosis*
  • Mucocutaneous Lymph Node Syndrome / drug therapy*
  • Treatment Outcome

Substances

  • Antibodies, Monoclonal
  • Immunologic Factors
  • Infliximab
  • Methylprednisolone