Pd(II)-catalyzed oxidative 1,1-diarylation of terminal olefins

Org Lett. 2010 Jun 18;12(12):2848-51. doi: 10.1021/ol1009575.

Abstract

Evaluation of the scope of a Pd(II)-catalyzed oxidative 1,1-diarylation reaction of terminal olefins using aryl stannanes is reported. The reaction is shown to be tolerant of functionality commonly encountered in organic synthesis; however, the reaction outcome was found to be dependent on the nature of the aryl stannane used. A mechanistic rationale for the observation of this influence is provided.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Alkenes / chemistry*
  • Catalysis
  • Molecular Structure
  • Oxidation-Reduction
  • Palladium / chemistry*

Substances

  • Alkenes
  • Palladium