'To prove this is the industry's best hope': big tobacco's support of research on the genetics of nicotine addiction

Addiction. 2010 Jun;105(6):974-83. doi: 10.1111/j.1360-0443.2010.02940.x.

Abstract

Background: New molecular techniques focus a genetic lens upon nicotine addiction. Given the medical and economic costs associated with smoking, innovative approaches to smoking cessation and prevention must be pursued; but can sound research be manipulated by the tobacco industry?

Methodology: The chronological narrative of this paper was created using iterative reviews of primary sources (the Legacy Tobacco Documents), supplemented with secondary literature to provide a broader context. The empirical data inform an ethics and policy analysis of tobacco industry-funded research.

Findings: The search for a genetic basis for smoking is consistent with industry's decades-long plan to deflect responsibility away from the tobacco companies and onto individuals' genetic constitutions. Internal documents reveal long-standing support for genetic research as a strategy to relieve the tobacco industry of its legal responsibility for tobacco-related disease.

Conclusions: Industry may turn the findings of genetics to its own ends, changing strategy from creating a 'safe' cigarette to defining a 'safe' smoker.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Conflict of Interest*
  • Deception
  • Documentation*
  • Genetic Predisposition to Disease
  • Genetic Research / economics
  • Humans
  • Lung Neoplasms / etiology
  • Male
  • Public Health
  • Research Support as Topic
  • Smoking / adverse effects
  • Smoking / genetics*
  • Smoking / psychology
  • Tobacco Industry* / ethics
  • Tobacco Industry* / legislation & jurisprudence
  • Tobacco Use Disorder / genetics*
  • Tobacco Use Disorder / psychology