New insight into cancer therapeutics: induction of differentiation by regulating the Musashi/Numb/Notch pathway

Cell Res. 2010 Oct;20(10):1083-5. doi: 10.1038/cr.2010.122. Epub 2010 Aug 31.

Authors

Yoshinori Nishimoto¹, Hideyuki Okano

Affiliation

¹ Department of Physiology, School of Medicine, Keio University, 35 Shinanomachi, Shinjuku, Tokyo 160-8582, Japan.

PMID: 20805843
DOI: 10.1038/cr.2010.122

No abstract available

MeSH terms

Cell Differentiation
Humans
Leukemia, Myelogenous, Chronic, BCR-ABL Positive / metabolism
Leukemia, Myelogenous, Chronic, BCR-ABL Positive / therapy
Membrane Proteins / metabolism*
Neoplasms / metabolism*
Neoplasms / therapy
Nerve Tissue Proteins / metabolism*
RNA-Binding Proteins / metabolism*
Receptors, Notch / metabolism*
Signal Transduction

Substances

MSI1 protein, human
MSI2 protein, human
Membrane Proteins
Nerve Tissue Proteins
NUMB protein, human
RNA-Binding Proteins
Receptors, Notch