Clinical factors analysis of curative effect of focused ultrasound treatment for non neoplastic epithelial disorders of vulva

Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2010 Sep;35(9):933-9. doi: 10.3969/j.issn.1672-7347.2010.09.006.

Abstract

Objective: To explore the related factors to influence the curative effect of focused ultrasound treatment for non neoplastic epithelial disorders of vulva.

Methods: A total of 382 patients with non neoplastic epithelial disorders of vulva were included in this study and treated by focused ultrasound. During and after the treatment, the symptoms and physical signs of the subjects were observed, and the efficacy was evaluated. We analyzed the relation between pathologic type, age, course, area, or itch degree and curative effect.

Results: Symptoms of all patients were relieved, and appearance and color of the vulva became normal after the ultrasound treatment, with a total effective rate of 99.74%. The cure ratios of patients with different pathologic types, ages, courses, areas, and itch degrees were significantly different (χ(2)=9.58, P<0.01; χ(2)=22.385, P<0.01; χ(2)=32.260, P<0.01; χ(2)=57.99,P<0.01; χ(2)=42.13,P<0.01, respectively).

Conclusion: Focused ultrasound treatment is safe and effective for the nonneoplastic epithelial disorders of the vulva and the efficacy is associated with the pathologic type, age, course, area, and itch degree.

Publication types

  • Clinical Trial

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Child
  • Female
  • High-Intensity Focused Ultrasound Ablation*
  • Humans
  • Hyperplasia / therapy
  • Middle Aged
  • Pruritus / therapy
  • Treatment Outcome
  • Vulva / pathology*
  • Vulvar Diseases / pathology
  • Vulvar Diseases / therapy*
  • Vulvar Lichen Sclerosus / pathology
  • Vulvar Lichen Sclerosus / therapy*
  • Young Adult