Influence of different regions of the H-2 complex on the rate of clearance of Salmonella typhimurium

Infect Immun. 1990 Feb;58(2):573-4. doi: 10.1128/iai.58.2.573-574.1990.

Abstract

The rate of clearance of Salmonella typhimurium from the mouse spleen is under H-2 linked genetic control. The results of the present study, with H-2 recombinant mice on a C57BL/10 background, suggest the involvement of at least two loci, one in the D region and the other in the K-A alpha chromosomal segment.

MeSH terms

  • Animals
  • Antigens, Differentiation, T-Lymphocyte / analysis
  • CD8 Antigens
  • Chromosome Mapping*
  • H-2 Antigens / genetics*
  • Mice
  • Mice, Inbred C57BL
  • Salmonella typhimurium / immunology*
  • Spleen / microbiology
  • T-Lymphocytes / immunology

Substances

  • Antigens, Differentiation, T-Lymphocyte
  • CD8 Antigens
  • H-2 Antigens