Familial cases of periodic fever with aphthous stomatitis, pharyngitis, and cervical adenitis syndrome

Masao Adachi; Aika Watanabe; Atsushi Nishiyama; Yoshinobu Oyazato; Ichiro Kamioka; Masanori Murase; Akihito Ishida; Hidemasa Sakai; Ryuta Nishikomori; Toshio Heike

doi:10.1016/j.jpeds.2010.09.054

Familial cases of periodic fever with aphthous stomatitis, pharyngitis, and cervical adenitis syndrome

J Pediatr. 2011 Jan;158(1):155-9. doi: 10.1016/j.jpeds.2010.09.054. Epub 2010 Nov 11.

Authors

Masao Adachi¹, Aika Watanabe, Atsushi Nishiyama, Yoshinobu Oyazato, Ichiro Kamioka, Masanori Murase, Akihito Ishida, Hidemasa Sakai, Ryuta Nishikomori, Toshio Heike

Affiliation

¹ Department of Pediatrics, Kakogawa Municipal Hospital, Kakogawa, Japan. ama-p@rc4.so-net.ne.jp

PMID: 21074183
DOI: 10.1016/j.jpeds.2010.09.054

Abstract

We report three familial cases of periodic fever with aphthous stomatitis, pharyngitis, and cervical adenitis syndrome, including a pair of monozygotic twins and their mother. It suggests that periodic fever with aphthous stomatitis, pharyngitis, and cervical adenitis syndrome may have a certain monogenetic background.

Publication types

Case Reports

MeSH terms

Adult
Child, Preschool
Female
Hereditary Autoinflammatory Diseases / complications
Hereditary Autoinflammatory Diseases / genetics*
Humans
Infant
Lymphadenitis / complications
Lymphadenitis / genetics*
Neck
Pharyngitis / complications
Pharyngitis / genetics*
Stomatitis, Aphthous / complications
Stomatitis, Aphthous / genetics*