Sentinel lymph node biopsy or nodal observation in melanoma: a prospective study of patient choices

Dermatol Surg. 2011 Feb;37(2):199-206. doi: 10.1111/j.1524-4725.2010.01855.x. Epub 2011 Jan 26.

Abstract

Background: There is no consensus regarding the therapeutic utility of sentinel lymph node biopsy (SLNB) versus that of nodal observation (NO) in melanoma.

Objective: To prospectively evaluate a standardized counseling procedure and its effect on patient choices to undergo SLNB or NO.

Methods: In four centers, patients with melanoma eligible for SLNB or NO received a complete counseling procedure that included verbal information from dermatologists and surgeons, a detailed information sheet, and a written consent form. Data collected included patient and tumor characteristics, counseling conditions, and specialties of informing doctors. Factors influencing patients' choices were studied using multivariate analysis.

Results: Of 343 consecutive patients, 309 were offered SLNB and NO and received complete verbal and written information from a dermatologist alone (62%) or in association with a surgeon (38%). Approximately half took advice from trusted persons, and half asked for additional time before making a decision; 268 (86.7%) ultimately decided to undergo SLNB. Multivariate analysis showed that older patients, those with a head and neck melanoma, and those informed without a surgeon present were more likely to prefer NO.

Conclusions: This counseling procedure was easily implemented in clinical practice. Patients favored SLNB but were able to understand uncertainties and express preferences.

Publication types

  • Multicenter Study

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Child
  • Directive Counseling
  • Female
  • Humans
  • Male
  • Melanoma / psychology*
  • Melanoma / secondary*
  • Middle Aged
  • Neoplasm Staging
  • Patient Acceptance of Health Care*
  • Patient Education as Topic
  • Prospective Studies
  • Sentinel Lymph Node Biopsy / statistics & numerical data*
  • Skin Neoplasms / pathology*
  • Skin Neoplasms / psychology*
  • Young Adult