Validation of plasma branched chain amino acids as biomarkers in Huntington disease

Arch Neurol. 2011 Feb;68(2):265-7. doi: 10.1001/archneurol.2010.358.
No abstract available

Publication types

  • Letter
  • Validation Study

MeSH terms

  • Adult
  • Aged
  • Amino Acids, Branched-Chain / blood*
  • Biomarkers / blood
  • Early Diagnosis
  • Female
  • Genotype
  • Heterozygote
  • Humans
  • Huntingtin Protein
  • Huntington Disease / blood*
  • Huntington Disease / diagnosis*
  • Huntington Disease / genetics
  • Isoleucine / blood
  • Leucine / blood
  • Linear Models
  • Male
  • Middle Aged
  • Nerve Tissue Proteins / genetics*
  • Nuclear Proteins / genetics*
  • Predictive Value of Tests
  • Severity of Illness Index
  • Trinucleotide Repeat Expansion*
  • Valine / blood

Substances

  • Amino Acids, Branched-Chain
  • Biomarkers
  • HTT protein, human
  • Huntingtin Protein
  • Nerve Tissue Proteins
  • Nuclear Proteins
  • Isoleucine
  • Leucine
  • Valine