Suprasellar tuberculoma presenting as panhypopituitarism

J Assoc Physicians India. 2010 Nov:58:706-9.

Abstract

Suprasellar tuberculomas are exceptionally rare. We present the case of a middle aged male who presented with generalised apathy and meningism of two weeks duration. Neuroimaging was suggestive of tuberculomas in suprasellar cistern, while endocrinological investigation showed panhypopituitarism manifesting as pituitary hypothyroidism, hypocortisolism, and hyperprolactinemia. Cerebrospinal fluid examination showed lymphocytic reaction with raised proteins. A diagnosis of suprasellar tuberculoma with panhypopituitarism was made. The patient was started on antituberculous treatment and hormone replacement which led to remarkable improvement in condition of patient and resolution of tuberculous granuloma in follow up imaging.

Publication types

  • Case Reports

MeSH terms

  • Antitubercular Agents / therapeutic use
  • Cerebrospinal Fluid
  • Diagnosis, Differential
  • Drug Therapy, Combination
  • Hormone Replacement Therapy
  • Humans
  • Hyperprolactinemia / diagnostic imaging
  • Hypopituitarism / diagnostic imaging
  • Hypopituitarism / etiology
  • Hypothyroidism
  • Magnetic Resonance Imaging
  • Male
  • Middle Aged
  • Tomography, X-Ray Computed
  • Tuberculoma, Intracranial / complications*
  • Tuberculoma, Intracranial / diagnosis*
  • Tuberculoma, Intracranial / drug therapy
  • Tuberculoma, Intracranial / pathology

Substances

  • Antitubercular Agents