Squalene synthase inhibitor lapaquistat acetate: could anything be better than statins?

Circulation. 2011 May 10;123(18):1925-8. doi: 10.1161/CIRCULATIONAHA.111.028571. Epub 2011 Apr 25.
No abstract available

Publication types

  • Comment
  • Editorial
  • Research Support, N.I.H., Extramural

MeSH terms

  • Anticholesteremic Agents / therapeutic use*
  • Cardiovascular Diseases / drug therapy
  • Cardiovascular Diseases / metabolism
  • Cardiovascular Diseases / prevention & control*
  • Farnesyl-Diphosphate Farnesyltransferase / antagonists & inhibitors*
  • Humans
  • Hydroxymethylglutaryl-CoA Reductase Inhibitors / therapeutic use*
  • Oxazepines / therapeutic use*
  • Piperidines / therapeutic use*

Substances

  • 1-((1-(3-acetoxy-2,2-dimethylpropyl)-7-chloro-5-(2,3-dimethoxyphenyl)-2-oxo-1,2,3,5-tetrahydro-4,1-benzoxazepin-3-yl)acetyl)piperidine-4-acetic acid
  • Anticholesteremic Agents
  • Hydroxymethylglutaryl-CoA Reductase Inhibitors
  • Oxazepines
  • Piperidines
  • Farnesyl-Diphosphate Farnesyltransferase