Cilostazol: a drug particularly effective for Asians?

Int J Stroke. 2011 Jun;6(3):209-10. doi: 10.1111/j.1747-4949.2011.00597.x.

Abstract

Cilostazol is an antiplatelet drug often used in Asia; however, it is rarely used in the western hemisphere, particularly for stroke patients. Further studies of cilostazol in other ethnicities are required to prove or disprove whether this drug is also beneficial in non-Asian populations.

MeSH terms

  • Aryl Hydrocarbon Hydroxylases / genetics
  • Asian People
  • Aspirin / therapeutic use
  • Cerebral Hemorrhage / complications
  • Cerebral Hemorrhage / drug therapy
  • Cerebrovascular Disorders / drug therapy
  • Cilostazol
  • Cytochrome P-450 CYP2C19
  • Humans
  • Intracranial Arteriosclerosis / drug therapy
  • Pharmacogenetics
  • Platelet Aggregation Inhibitors / therapeutic use*
  • Tetrazoles / therapeutic use*
  • Treatment Outcome

Substances

  • Platelet Aggregation Inhibitors
  • Tetrazoles
  • Aryl Hydrocarbon Hydroxylases
  • CYP2C19 protein, human
  • Cytochrome P-450 CYP2C19
  • Cilostazol
  • Aspirin