Don't be a clot: a radiologist's guide to haemostasis including novel antiplatelet and anticoagulant therapies

E M Godfrey; A L Godfrey; D J Perry; A S Shaw

doi:10.1016/j.crad.2011.03.014

Don't be a clot: a radiologist's guide to haemostasis including novel antiplatelet and anticoagulant therapies

Clin Radiol. 2011 Aug;66(8):693-700. doi: 10.1016/j.crad.2011.03.014. Epub 2011 May 20.

Authors

E M Godfrey¹, A L Godfrey, D J Perry, A S Shaw

Affiliation

¹ Department of Radiology, Addenbrooke's Hospital, Cambridge, UK. edgodfrey@doctors.net.uk

PMID: 21601183
DOI: 10.1016/j.crad.2011.03.014

Abstract

Normal haemostasis relies on the complex interactions of the coagulation cascade, platelets, and the endothelium. In this review, the roles of each of these elements are described as well as common causes for their derangement. Haemostasis may be manipulated via pharmacological means and in recent years there has been a significant increase in the number of agents available for influencing haemostatic mechanisms. It is essential that radiologists are aware of these mechanisms and drugs if they are to perform image-guided procedures safely. In addition to describing the relevant pathways and drugs, practical tips are provided.

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Anticoagulants / pharmacology
Blood Coagulation Disorders / etiology
Blood Coagulation* / drug effects
Blood Coagulation* / physiology
Blood Coagulation* / radiation effects
Blood Platelets / physiology
Endothelium, Vascular* / drug effects
Endothelium, Vascular* / physiology
Endothelium, Vascular* / radiation effects
Hemostasis* / drug effects
Hemostasis* / physiology
Hemostasis* / radiation effects
Humans
Platelet Aggregation Inhibitors / therapeutic use
Practice Guidelines as Topic
Prothrombin Time
Radiology, Interventional / methods
Radiology, Interventional / standards
Thrombocytopenia / etiology

Substances

Anticoagulants
Platelet Aggregation Inhibitors