Soft tissue myoepithelioma of the scalp in a 11-year-old girl: a challenging diagnosis

Pediatr Dermatol. 2012 May-Jun;29(3):345-8. doi: 10.1111/j.1525-1470.2011.01428.x. Epub 2011 May 25.

Abstract

Myoepithelioma is a well-known tumor in the salivary glands and breasts in adults. It is exceptionally rare in soft tissue and in children. We present a case of subcutaneous scalp myoepithelioma in an 11-year-old girl. On clinical examination, it appeared as a dermoid cyst. Myoepithelioma is uncommon in the subcutaneous tissue. Clinically, the neoplasm is nonspecific. Because of the variable appearance of myoepithelial cells and their phenotype, the pathological diagnosis is challenging. We report a case of subcutaneous myoepithelioma in a child and discuss the literature.

Publication types

  • Case Reports

MeSH terms

  • 12E7 Antigen
  • Antigens, CD / analysis
  • Cell Adhesion Molecules / analysis
  • Child
  • Chromosomal Proteins, Non-Histone / analysis
  • DNA-Binding Proteins / analysis
  • Dermoid Cyst / pathology
  • Diagnostic Errors
  • Female
  • Glial Fibrillary Acidic Protein / analysis
  • Head and Neck Neoplasms / pathology*
  • Head and Neck Neoplasms / surgery
  • Humans
  • Myoepithelioma / pathology*
  • Myoepithelioma / surgery
  • S100 Proteins / analysis
  • SMARCB1 Protein
  • Scalp / pathology*
  • Scalp / surgery
  • Skin Neoplasms / pathology*
  • Skin Neoplasms / surgery
  • Transcription Factors / analysis
  • Treatment Outcome
  • Vimentin / analysis

Substances

  • 12E7 Antigen
  • Antigens, CD
  • CD99 protein, human
  • Cell Adhesion Molecules
  • Chromosomal Proteins, Non-Histone
  • DNA-Binding Proteins
  • Glial Fibrillary Acidic Protein
  • S100 Proteins
  • SMARCB1 Protein
  • SMARCB1 protein, human
  • Transcription Factors
  • Vimentin