Laser therapy for twin-to-twin transfusion syndrome (TTTS)

Prenat Diagn. 2011 Jul;31(7):637-46. doi: 10.1002/pd.2803. Epub 2011 Jun 9.

Abstract

Monochorionic twins are subjected to specific complications which originate in either imbalance or abnormality of the single placenta serving two twins including twin-to-twin transfusion syndrome. The diagnosis is well established in overt clinical forms with the association of polyuric polyhydramnios and oliguric oligohydramnios. The best treatment of cases presenting before 26 weeks of gestion is fetoscopic laser ablation of the intertwin anastomoses on the chorionic plate. Although subjected to subtle variations, the core technique follows robust guidelines which could help understanding and acquiring the required skills and experience to perform this procedure. However appropriate and tailored hands-on training and appropriate perinatal set-up are critical not only for surgical management but also for the follow-up and management of related complications.

Publication types

  • Review

MeSH terms

  • Female
  • Fetofetal Transfusion / surgery*
  • Fetoscopy / adverse effects
  • Fetoscopy / instrumentation
  • Fetoscopy / methods*
  • Humans
  • Laser Therapy / adverse effects
  • Laser Therapy / instrumentation
  • Laser Therapy / methods*
  • Learning Curve
  • Models, Biological
  • Perioperative Period / methods
  • Postoperative Complications / etiology
  • Pregnancy