Detection of Mycoplasma genitalium-reactive cervicovaginal antibodies among infected women

Clin Vaccine Immunol. 2011 Oct;18(10):1783-6. doi: 10.1128/CVI.05174-11. Epub 2011 Aug 3.

Abstract

Mycoplasma genitalium-reactive cervicovaginal IgA and IgG antibodies were detected in 51.9% and 70.4% of 27 infected women and 22.2% and 18.5% of 27 uninfected controls, respectively. The predominance of MgpB- and MgpC-reactive antibodies at the site of infection is consistent with their hypothesized role in selecting antigenic variants during persistent infection.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Antibodies, Bacterial / analysis*
  • Antigens, Bacterial
  • Cervix Uteri / immunology*
  • Female
  • Humans
  • Immunoglobulin A / analysis
  • Immunoglobulin G / analysis
  • Mycoplasma Infections / immunology*
  • Mycoplasma genitalium / immunology*
  • Vagina / immunology*
  • Vaginal Douching

Substances

  • Antibodies, Bacterial
  • Antigens, Bacterial
  • Immunoglobulin A
  • Immunoglobulin G