microRNA-10b: a new marker or the marker of pancreatic ductal adenocarcinoma?

Tetsuro Setoyama; Xinna Zhang; Shoji Natsugoe; George A Calin

doi:10.1158/1078-0432.CCR-11-1477

microRNA-10b: a new marker or the marker of pancreatic ductal adenocarcinoma?

Clin Cancer Res. 2011 Sep 1;17(17):5527-9. doi: 10.1158/1078-0432.CCR-11-1477. Epub 2011 Aug 4.

Authors

Tetsuro Setoyama¹, Xinna Zhang, Shoji Natsugoe, George A Calin

Affiliation

¹ Department of Experimental Therapeutics and Cancer Biology and Center for RNA Interference and Non-Coding RNAs, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.

PMID: 21816909
DOI: 10.1158/1078-0432.CCR-11-1477

Abstract

microRNA-10b (miR-10b) expression in pancreatic ductal adenocarcinoma (PDAC), as identified by in situ hybridization, is highly correlated with cancer diagnosis, therapy response, and prognosis. If these findings are further confirmed in prospective studies, miR-10b could be used to improve the management of PDAC and decrease the mortality rate of this deadly cancer.

Publication types

Research Support, Non-U.S. Gov't
Comment

MeSH terms

Carcinoma, Pancreatic Ductal / drug therapy*
Female
Humans
Male
MicroRNAs / genetics*
Pancreatic Neoplasms / drug therapy*

Substances

MIRN10 microRNA, human
MicroRNAs