Phosphorylated H2Ax is not an unambiguous marker for DNA double-strand breaks

Cell Cycle. 2011 Oct 1;10(19):3223-4. doi: 10.4161/cc.10.19.17448. Epub 2011 Oct 1.

Authors

James E Cleaver, Luzviminda Feeney, Ingrid Revet

PMID: 21921674
DOI: 10.4161/cc.10.19.17448

No abstract available

Publication types

Editorial

MeSH terms

Apoptosis
Ataxia Telangiectasia Mutated Proteins
Cell Cycle Proteins / metabolism
DNA Breaks, Double-Stranded
DNA Repair
DNA-Binding Proteins / metabolism
Histones / genetics
Histones / metabolism*
Humans
Phosphorylation
Protein Serine-Threonine Kinases / metabolism
S Phase Cell Cycle Checkpoints
Tumor Suppressor Proteins / metabolism

Substances

Cell Cycle Proteins
DNA-Binding Proteins
H2AX protein, human
Histones
Tumor Suppressor Proteins
ATM protein, human
ATR protein, human
Ataxia Telangiectasia Mutated Proteins
Protein Serine-Threonine Kinases