Hyperreninemic hypertension following presumed abdominal trauma

Nat Rev Nephrol. 2011 Sep 27;7(12):730-4. doi: 10.1038/nrneph.2011.127.

Abstract

Background: An 18-year-old previously normotensive man was referred to a hypertension unit with blood pressure readings of 140-150/100-110 mmHg. Renal ultrasound had shown a right renal subcapsular fluid collection and an abdominal computed tomography scan had revealed a large cystic lesion surrounding the right kidney with a thick wall and irregular peripheral calcification consistent with a long-standing traumatic perinephric hematoma.

Investigations: Physical examination, renal artery duplex ultrasonography, magnetic resonance imaging of the abdomen, isotopic renography with technetium-99m diethylenetriamine pentaacetic acid, and a renal venous renin ratio study.

Diagnosis: Hyperreninemic hypertension as a result of presumed abdominal trauma.

Management: Removal of the affected kidney.

Publication types

  • Case Reports

MeSH terms

  • Abdominal Injuries / blood
  • Abdominal Injuries / complications*
  • Abdominal Injuries / diagnosis
  • Adolescent
  • Biomarkers / blood
  • Blood Pressure
  • Diagnosis, Differential
  • Humans
  • Hypertension / blood
  • Hypertension / diagnosis
  • Hypertension / etiology*
  • Magnetic Resonance Imaging
  • Male
  • Radioisotope Renography
  • Renal Artery / injuries*
  • Renin / blood*
  • Tomography, X-Ray Computed
  • Trauma Severity Indices

Substances

  • Biomarkers
  • Renin