Objective: To study the meaning of expressions of ENO1 in the nasopharyngeal cancer tissue.
Method: By using SP immunohistochemical methods.
Result: The positive expressions for ENO1 were 60.0% in the nasopharyngeal cancer tissues,significantly higher than that (27.5%, 11/40) of in inflammatory nasopharyngeal mucosa (P<0.05). The positive expression rate of ENO1 protein in stage T1 + T2 + T3 was higher than that of in patients with T4 (chi2 = 11.424, P<0.05). But there was no significant relationship between expression of ENO1 and lymph node metastasis and postradiotherapy distant metastasis (P>0.05).
Conclusion: The results show that ENO1 over expression may play a important role in cell proliferation and canceration of nasopharyngeal cancer.