Abstract
The bla(OXA-51)-like gene, originally intrinsic to Acinetobacter baumannii, had been detected in two clones of Acinetobacter nosocomialis and one clone of Acinetobacter genomic species "Close to 13TU." These bla(OXA-51)-like genes, all preceded by ISAba1, were located on plasmids that might have originated with A. baumannii. The plasmid-borne ISAba1--bla(OXA-51)-like confers a high level of carbapenem resistance and affects the accuracy of using bla(OXA-51)-like detection as a tool for differentiating A. baumannii from other Acinetobacter species.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Acinetobacter / classification
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Acinetobacter / drug effects*
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Acinetobacter / enzymology
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Acinetobacter / genetics
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Acinetobacter Infections / epidemiology
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Acinetobacter Infections / microbiology
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Acinetobacter baumannii / drug effects
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Acinetobacter baumannii / enzymology
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Acinetobacter baumannii / genetics
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Adult
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Aged
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Aged, 80 and over
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Anti-Bacterial Agents / pharmacology*
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Bacteremia / epidemiology
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Bacteremia / microbiology
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Bacterial Proteins / genetics
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Bacterial Proteins / metabolism
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Carbapenems / pharmacology*
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Cross Infection / epidemiology*
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Cross Infection / microbiology
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Drug Resistance, Bacterial*
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Electrophoresis, Gel, Pulsed-Field
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Female
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Humans
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Male
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Microbial Sensitivity Tests
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Molecular Sequence Data
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Plasmids / genetics
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Sequence Analysis, DNA
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Taiwan / epidemiology
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Young Adult
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beta-Lactamases / genetics*
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beta-Lactamases / metabolism
Substances
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Anti-Bacterial Agents
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Bacterial Proteins
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Carbapenems
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beta-Lactamases
Associated data
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GENBANK/HQ425492
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GENBANK/HQ425493
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GENBANK/HQ425494
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GENBANK/HQ425495