Three cases of acute gastroenteritis caused by high-level macrolideresistant Campylobacter: drug resistance mechanisms and clinical characteristics

Jie Chen; Yanyan Yu; Jun Wang; Yixing Gu; Xinting Sun; Jinghang Xu; Zheng Zeng

doi:10.3109/00365548.2012.656319

Three cases of acute gastroenteritis caused by high-level macrolideresistant Campylobacter: drug resistance mechanisms and clinical characteristics

Scand J Infect Dis. 2012 Jul;44(7):541-3. doi: 10.3109/00365548.2012.656319. Epub 2012 Mar 4.

Authors

Jie Chen¹, Yanyan Yu, Jun Wang, Yixing Gu, Xinting Sun, Jinghang Xu, Zheng Zeng

Affiliation

¹ Department of Infectious Diseases, Peking University First Hospital, Beijing, China.

PMID: 22385190
DOI: 10.3109/00365548.2012.656319

Abstract

We report 3 cases of acute gastroenteritis caused by high-level macrolide-resistant Campylobacter. The clinical characteristics of patients were studied, and the rplD, rplV, and 23S rRNA domain V genes were sequenced to detected resistance-related mutations.

Publication types

Case Reports

MeSH terms

Aged
Anti-Bacterial Agents / pharmacology*
Campylobacter / drug effects*
Campylobacter / isolation & purification
Campylobacter Infections / microbiology*
Campylobacter Infections / pathology
DNA, Bacterial / chemistry
DNA, Bacterial / genetics
Drug Resistance, Bacterial
Female
Gastroenteritis / microbiology*
Gastroenteritis / pathology
Genes, Bacterial
Humans
Macrolides / pharmacology*
Male
Middle Aged
Mutation
Sequence Analysis, DNA

Substances

Anti-Bacterial Agents
DNA, Bacterial
Macrolides