One in 10 million: a case of cleidocranial dysplasia and acute lymphoblastic leukaemia--more than just a coincidence?

Clin Dysmorphol. 2012 Jul;21(3):170-171. doi: 10.1097/MCD.0b013e32835431fd.

Authors

Alice Gardham¹, Elizabeth Forsythe, Nick Goulden

Affiliation

¹ NW Thames Regional Genetics Service, Harrow, Middlesex Institute of Child Health, London Department of Haematology and Oncology, Great Ormond Street Hospital, London, UK.

PMID: 22569278
DOI: 10.1097/MCD.0b013e32835431fd

No abstract available

Publication types

Case Reports

MeSH terms

Child, Preschool
Cleidocranial Dysplasia / complications
Cleidocranial Dysplasia / diagnosis*
Cleidocranial Dysplasia / genetics
Core Binding Factor Alpha 1 Subunit / genetics*
Core Binding Factor Alpha 2 Subunit / genetics
ETS Translocation Variant 6 Protein
Exons
Gene Rearrangement
Genetic Testing
Germ-Line Mutation
Humans
Infant
Male
Mutation, Missense
Precursor Cell Lymphoblastic Leukemia-Lymphoma / complications
Precursor Cell Lymphoblastic Leukemia-Lymphoma / diagnosis*
Precursor Cell Lymphoblastic Leukemia-Lymphoma / genetics
Proto-Oncogene Proteins c-ets / genetics
Repressor Proteins / genetics

Substances

Core Binding Factor Alpha 1 Subunit
Core Binding Factor Alpha 2 Subunit
Proto-Oncogene Proteins c-ets
RUNX1 protein, human
RUNX2 protein, human
Repressor Proteins