Treatment of hypergranulation tissue with high potency topical corticosteroids in children

Pediatr Dermatol. 2012 Sep-Oct;29(5):675-8. doi: 10.1111/j.1525-1470.2012.01724.x. Epub 2012 May 21.

Abstract

Hypergranulation is having more granulation tissue than needed to fill a wound defect. Some pediatric dermatologists and most dermatologic surgeons will encounter this complication during their careers. Associated factors include wound site, prolonged inflammation, an imbalance in matrix metalloproteinases, and excessive angiogenesis. Reported treatments have included silver nitrate, excision, laser ablation, and topical corticosteroids. Our case series supports the use of medium- to high-potency topical corticosteroids in the treatment of hypergranulation tissue.

Publication types

  • Case Reports

MeSH terms

  • Administration, Topical
  • Adrenal Cortex Hormones / therapeutic use*
  • Child
  • Child, Preschool
  • Granulation Tissue / drug effects*
  • Granulation Tissue / pathology*
  • Humans
  • Male
  • Treatment Outcome
  • Wound Healing / drug effects*

Substances

  • Adrenal Cortex Hormones