Aim: To train Tibetan monkey (Macaca thibetana) for intraocular pressure (IOP) measurement in conscious state and obtain normal IOP in conscious Tibetan Macaque.
Methods: The training was based on award-conditioned behavior. Food stimulation and human-animal interaction were used in this training.
Results: Trained Tibetan monkeys calmly accepted IOP measurement by the TonoVet® rebound tonometer without sedation or anesthesia and their IOP values were similar to other primates.
Conclusion: Human-cultivated Thibetan monkeys are tamable, and can be used for biomedical research such as ophthalmic research without anesthesia.
Keywords: Macaca thibetana; conscious intraocular pressure measurement; domestication.