Angioneurotic orolingual oedema following thrombolysis in acute ischaemic stroke

D Wallon; P Girardie; S Bombois; C Lucas

doi:10.1136/bcr.06.2010.3094

Angioneurotic orolingual oedema following thrombolysis in acute ischaemic stroke

BMJ Case Rep. 2010 Oct 21:2010:bcr0620103094. doi: 10.1136/bcr.06.2010.3094.

Authors

D Wallon¹, P Girardie, S Bombois, C Lucas

Affiliation

¹ Department of Neurology, Memory Center, Lille University Hospital, Lille, France.

Abstract

Alteplase used for thrombolysis in ischaemic stroke may be complicated by orolingual acute angioedema (OAA), a rare but potentially life-threatening side effect. We report the case of a 32-year-old woman who over 24 h experienced OAA after thrombolysis for an acute ischaemic left hemispheric stroke. We discuss the pathophysiology of this rare phenomenon.

Publication types

Case Reports

MeSH terms

Adult
Angioedema / chemically induced*
Angioedema / diagnosis
Female
Fibrinolytic Agents / adverse effects*
Fibrinolytic Agents / therapeutic use
Humans
Stroke / drug therapy*
Tissue Plasminogen Activator / adverse effects*
Tissue Plasminogen Activator / therapeutic use
Tongue Diseases / chemically induced*
Tongue Diseases / diagnosis

Substances

Fibrinolytic Agents
Tissue Plasminogen Activator