NETs tangle with HIV

Craig N Jenne; Paul Kubes

doi:10.1016/j.chom.2012.07.002

NETs tangle with HIV

Cell Host Microbe. 2012 Jul 19;12(1):5-7. doi: 10.1016/j.chom.2012.07.002.

Authors

Craig N Jenne¹, Paul Kubes

Affiliation

¹ Calvin, Phoebe & Joan Snyder Institute for Chronic Diseases, University of Calgary, Alberta, Canada.

PMID: 22817983
DOI: 10.1016/j.chom.2012.07.002

Abstract

Neutrophil extracellular traps (NETs) are comprised of extracellular DNA coated in cytotoxic proteins capable of ensnaring and killing bacteria. Saitoh et al. (2012) expand our understanding of NETs into antiviral immunity by demonstrating that HIV induces the formation of NETs, which can bind and neutralize viral particles.

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