Evaluation of longitudinal clinical outcomes and adherence to care among HIV-infected refugees

J Int Assoc Provid AIDS Care. 2013 May-Jun;12(3):202-7. doi: 10.1177/1545109712459680. Epub 2012 Sep 28.

Abstract

Background: HIV-infected refugees resettled in the United States face many challenges. Longitudinal data regarding HIV-specific outcomes in this population are limited.

Methods: We reviewed charts of 51 HIV-infected sub-Saharan African refugees matched to 102 nonrefugees. Outcomes analyzed included CD4 counts, viral loads (VLs), antiretroviral treatment (ART) use, appointment adherence, opportunistic infections, and resistance mutations.

Results: The ART initiation was similar. Appointment adherence was similar in year 1, but refugees were significantly less adherent beyond year 3. Refugees and nonrefugees spent similar amounts of time in care suppressed (83% vs 80%, P = .93). Refugees had higher odds of viremia following undetectable VL (OR 2.3, P < .05).

Discussion: Initially, sub-Saharan African HIV-infected refugees have comparable appointment adherence, ART use, and VL suppression to nonrefugees. Overtime refugees were less adherent to appointments and more likely to have postsuppression viremia. The support services provided to refugees early in care may be important for retention in care and treatment success.

Keywords: HIV; clinic adherence; postsuppression viremia; refugee; sub-Saharan Africa.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Adolescent
  • Adult
  • Africa South of the Sahara / ethnology
  • Aged
  • Anti-HIV Agents / therapeutic use
  • Appointments and Schedules
  • Female
  • HIV Infections / ethnology*
  • HIV Infections / psychology
  • HIV Infections / therapy*
  • Health Knowledge, Attitudes, Practice
  • Humans
  • Longitudinal Studies
  • Male
  • Middle Aged
  • Patient Compliance*
  • Refugees*
  • Socioeconomic Factors
  • Treatment Outcome
  • United States / epidemiology
  • Young Adult

Substances

  • Anti-HIV Agents