Depression with psychotic features in a child with SLE: successful therapy with psychotropic medications--case report

Eur Child Adolesc Psychiatry. 2013 Apr;22(4):247-50. doi: 10.1007/s00787-012-0330-5. Epub 2012 Oct 10.

Abstract

Systemic lupus erythematosus (SLE) is a multisystemic, autoimmune disease of unknown etiology, which affects multiple organ systems, including the central nervous system (CNS). Neuropsychiatric manifestations are seen in 13-75% of all SLE patients, with equal frequency in children and adults. Despite a high prevalence of psychiatric manifestations, there is no consensus on the proper treatment of such cases. We report here a case of an 11-year-old girl diagnosed with a severe depressive episode with psychotic features, treated successfully with risperidone and sertraline as an adjunct to immunosuppressive therapy.

Publication types

  • Case Reports

MeSH terms

  • Anti-Anxiety Agents / therapeutic use*
  • Antipsychotic Agents / therapeutic use*
  • Child
  • Depression / complications*
  • Depression / drug therapy
  • Depression / psychology
  • Diazepam / therapeutic use*
  • Female
  • Humans
  • Lupus Erythematosus, Systemic / complications*
  • Lupus Erythematosus, Systemic / psychology
  • Psychotic Disorders / complications*
  • Psychotic Disorders / drug therapy
  • Psychotic Disorders / psychology
  • Risperidone / therapeutic use*
  • Treatment Outcome

Substances

  • Anti-Anxiety Agents
  • Antipsychotic Agents
  • Risperidone
  • Diazepam