Human immunodeficiency virus wasting syndrome may represent a treatable myopathy

Neurology. 1990 Mar;40(3 Pt 1):535-8. doi: 10.1212/wnl.40.3_part_1.535.

Abstract

We evaluated 5 patients with the diagnosis of HIV wasting syndrome. None had severe diarrhea or other causes for malabsorption. All had myopathy by clinical, laboratory, and muscle biopsy criteria. Withdrawal of azidothymidine in 3 patients did not lead to improvement. Corticosteroid therapy was effective in 3 patients.

MeSH terms

  • Acquired Immunodeficiency Syndrome / physiopathology
  • Adult
  • HIV Infections / physiopathology*
  • HIV Seropositivity / physiopathology
  • Humans
  • Middle Aged
  • Muscular Diseases / drug therapy*
  • Muscular Diseases / physiopathology
  • Prednisone / administration & dosage
  • Time Factors
  • Weight Loss
  • Zidovudine / administration & dosage

Substances

  • Zidovudine
  • Prednisone