[Case report: Purulent pericarditis caused by candida species--a rare but life-threatening disease in intensive care medicine]

Anasthesiol Intensivmed Notfallmed Schmerzther. 2013 Mar;48(3):144-9. doi: 10.1055/s-0033-1342897. Epub 2013 Apr 15.
[Article in German]

Abstract

We report a case of a male patient with drug abuse in his medical history who was hospitalized because of a community acquired pneumonia. Subsequently the patient developed an acute lung injury (ARDS) and a fulminant purulent pericarditis accompanied by a pericardial effusion. Caused by the pericardial tamponade cardiac function was severely restricted. Due to fast diagnosis and immediate adequate therapy such as systemic anti-fungal treatment, pericardiocentesis, percutaneous drainage, and later surgical intervention the patient was treated successfully. This article describes etiology, pathophysiology and symptoms of purulent Candida-pericarditis and gives a review of existing literature regarding this extremely rare disease. In addition therapeutic options are discussed.

Publication types

  • Case Reports

MeSH terms

  • Amphotericin B / therapeutic use
  • Antifungal Agents / therapeutic use
  • Candida glabrata*
  • Candidiasis / microbiology*
  • Candidiasis / surgery
  • Candidiasis / therapy*
  • Caspofungin
  • Community-Acquired Infections / microbiology
  • Community-Acquired Infections / therapy
  • Critical Care*
  • Drainage
  • Echinocandins / therapeutic use
  • Emergency Medical Services
  • Humans
  • Lipopeptides
  • Male
  • Middle Aged
  • Pericardiocentesis
  • Pericarditis / microbiology*
  • Pericarditis / surgery
  • Pericarditis / therapy*
  • Prognosis
  • Respiratory Distress Syndrome / etiology
  • Respiratory Distress Syndrome / therapy
  • Substance-Related Disorders / complications
  • Treatment Outcome

Substances

  • Antifungal Agents
  • Echinocandins
  • Lipopeptides
  • Amphotericin B
  • Caspofungin