A superquenched DNAzyme-perylene complex: a convenient, universal and low-background strategy for fluorescence catalytic biosensors

Chem Commun (Camb). 2013 Jul 28;49(59):6644-6. doi: 10.1039/c3cc43054e.

Abstract

Taking advantage of the super-quenching effect of the cationic perylene derivative on adjacent fluorophores, we for the first time reported a DNAzyme-perylene complex-based strategy for constructing fluorescence catalytic biosensors with improved sensitivity.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Biosensing Techniques*
  • Catalysis
  • DNA, Catalytic / chemistry*
  • DNA, Catalytic / metabolism
  • Fluorescence*
  • Molecular Structure
  • Perylene / chemistry*
  • Spectrometry, Fluorescence

Substances

  • DNA, Catalytic
  • Perylene