Enhanced catalytic activity in organic solvents using molecularly dispersed haemoglobin-polymer surfactant constructs

Yixiong Zhang; Avinash J Patil; Adam W Perriman; Stephen Mann

doi:10.1039/c3cc46101g

Enhanced catalytic activity in organic solvents using molecularly dispersed haemoglobin-polymer surfactant constructs

Chem Commun (Camb). 2013 Oct 25;49(83):9561-3. doi: 10.1039/c3cc46101g.

Authors

Yixiong Zhang¹, Avinash J Patil, Adam W Perriman, Stephen Mann

Affiliation

¹ Centre for Organized Matter Chemistry, School of Chemistry, University of Bristol, Bristol BS8 1TS, UK. chawp@bristol.ac.uk avinash.patil@bristol.ac.uk.

PMID: 24018483
DOI: 10.1039/c3cc46101g

Abstract

The surface of haemoglobin (Hb) is chemically modified to produce molecular dispersions of discrete core-shell Hb-polymer surfactant bionanoconjugates in water and organic solvents. The hybrid nanoconstructs exhibit peroxidase-like catalytic activity with enhanced turnover rates compared with native Hb in water.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Catalysis
Hemoglobins / chemistry*
Hemoglobins / metabolism
Hydrogen Peroxide / metabolism
Models, Molecular
Nanostructures / chemistry*
Peroxidase / chemistry*
Peroxidase / metabolism
Polymers / chemistry*
Solvents / chemistry
Surface Properties
Surface-Active Agents / chemistry*
Water / chemistry

Substances

Hemoglobins
Polymers
Solvents
Surface-Active Agents
Water
Hydrogen Peroxide
Peroxidase