Reactivation of Chagas disease in a bone marrow transplant patient: case report and review of screening and management

Transpl Infect Dis. 2013 Dec;15(6):E264-7. doi: 10.1111/tid.12157. Epub 2013 Oct 23.

Abstract

We report a patient with an autologous stem cell transplant and history of residence in a Chagas disease (CD) endemic area who developed Chagas reactivation after induction for transplantation. We recommend that patients at risk for CD be screened before transplantation, and patients found to have chronic infection be monitored for reactivation post transplant.

Keywords: Chagas disease; Trypanosoma cruzi; parasites; reactivation Chagas; stem cell transplant; transplant.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Antibodies, Protozoan / blood*
  • Bone Marrow Transplantation*
  • Chagas Disease / blood
  • Chagas Disease / diagnosis*
  • Female
  • Humans
  • Middle Aged
  • Multiple Myeloma / therapy
  • Polymerase Chain Reaction
  • Recurrence
  • Transplantation Conditioning / adverse effects*
  • Trypanosoma cruzi / genetics
  • Trypanosoma cruzi / immunology*

Substances

  • Antibodies, Protozoan