Spindle cell carcinoma of the larynx presenting as a vocal fold cyst

Amy L Rutt; Ignacio Mintz; Christina Jackson-Menaldi; Michael Johns; Jonathan B McHugh; Adam D Rubin

doi:10.1016/j.jvoice.2013.10.013

Spindle cell carcinoma of the larynx presenting as a vocal fold cyst

J Voice. 2014 Jul;28(4):524.e9-524.e11. doi: 10.1016/j.jvoice.2013.10.013. Epub 2013 Nov 5.

Authors

Amy L Rutt¹, Ignacio Mintz², Christina Jackson-Menaldi³, Michael Johns⁴, Jonathan B McHugh⁵, Adam D Rubin⁶

Affiliations

¹ Department of Otolaryngology-Head and Neck Surgery, Detroit Medical Center, Michigan State University, Detroit, Michigan. Electronic address: Scse9000@aol.com.
² Department of Otolaryngology-Head and Neck Surgery, Trauma and Emergency Hospital, Malvinas Argentinas, Buenos Aires, Argentina.
³ Lakeshore Professional Voice Center, Lakeshore Ear, Nose and Throat Center, Saint Claire Shores, Michigan; Department of Otolaryngology-Head and Neck Surgery, Wayne State University School of Medicine, Detroit, Michigan.
⁴ Department of Otolaryngology-Head and Neck Surgery, Emory University School of Medicine, Atlanta, Georgia.
⁵ Department of Pathology, University of Michigan Medical Center, Ann Arbor, Michigan.
⁶ Lakeshore Professional Voice Center, Lakeshore Ear, Nose and Throat Center, Saint Claire Shores, Michigan; Department of Otolaryngology-Head and Neck Surgery, University of Michigan Medical Center, Ann Arbor, Michigan.

PMID: 24210722
DOI: 10.1016/j.jvoice.2013.10.013

Abstract

Spindle cell carcinoma (SPCC) is a rare, malignant variant of squamous cell carcinoma (SCC), which shows biphasic proliferation of the conventional SCC component and malignant spindle shape cells with sarcomatous appearance. We present two cases of SPCC of the true vocal fold that presented as a benign appearing subepithelial mass. We discuss the patient presentation, voice assessment, surgical treatment, and a review of the literature.

Keywords: Dysphonia; Laryngeal cancer; Spindle cell; Vocal fold carcinoma.

Publication types

Case Reports
Review

MeSH terms

Aged
Carcinoma / pathology*
Carcinoma, Squamous Cell / pathology
Cysts / pathology*
Diagnosis, Differential
Humans
Laryngeal Neoplasms / pathology*
Male
Middle Aged
Vocal Cords / pathology*